Moclobemide or bupropion

moclobemide or bupropion

Tl:Dr at bottom.

I've tried escitalopram and venlafaxine for depression/anhedonia which didn't do much for me.

Now I was looking for a new kind of antidepressant to try considering I've already tried SSRI and SNRI.

I stumbled upon moclobemide which seemed appealing because, if I understand correctly, it is better tolerated than TCAs, works quite quickly, has no sexual side effects (even reports of increased libido), low risk of toxicity and is effective at treating depression.

I suggested this to my psychiatrist and she said she was not too familiar with this drug and said that MAOI generally have a lot of side effects as well as complications with high blood pressure. She also checked her guidelines and said moclobemide isn't even in the guidelines for depression.
She suggested to instead try nortriptyline or bupropion.

I can be quite stubborn, but I got the impression that she didn't know enough about moclobemide to fairly consider it as an option.


Tl:dr; psychiatrist seems uninformed/misinformed about moclobemide which I'd like to try.
Should I insist on wanting to try it or accept her advice to try bupropion?

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Trust the woman that spent 12 years going to medical school user.

She literally said that she didn't know much about the drug and she said things that directly contradict the info that I can find in studies

People who have studied a lot are not infallible

Dork

.

hey person, i see yr not joking. i easily found this...

Is moclobemide a good antidepressant?
Conclusion: Moclobemide is an effective antidepressant and is better tolerated than imipramine.

if your in cali you are fucked they are literally passing a law that you cant even think different than "they" tell you you to.Of course this law is to fuck people up with c19 mrna shit. but drs cant even think anymore. and yeah dude psychs, the ones who prescribe meds, literally dont know shit. they jsut sit and prescibe, then when some pharma company pays fda enough they say this med is the new solution.

fyi, bupropion, welbutron is absolutely shit. there is a honeymoon phase but it doesnt work for shit. ofc ivermectin cannot be used for anything anymore, not even jsut off label, welbutrin is only off label. quit smoking? lose weight? sure why not. it doesnt work.

did you know new studies show that depression, there isnt even proof there is a "chemical imbalance"? Also, dont trust therapy, unless youve been raped as a kid. but then they will just pill you up. i dont believe in shit, fuck anything in the realm of "mindfulness" but you just have to concur it.

Just start powerlifting you fucking bitch

Ask for Adderall/Ritalin. "Antidepressants" are all placebo, stimulants is where its at.

im sorta drunk but sincere. tell here why yr so sad? or do you just, like my partner, want an easy fix?

Weird how on one hand you use "studies" as argument that there is no chemical imbalance yet at the same time don't pay attention to the overwhelming amount of studies that show medication and therapy are both effective at treating depression.

I already do, nigger
You don't know shit

>Antidepressants" are all placebo,
?????
Double blind studies with placebo say otherwise.

No particular reason, been feeling depressed most my life.
No I don't want an easy fix. I've tried just about everything under the sun except medication.
This is kind of a last resort sorta thing

dont fight, why? i said new research. old research is old. why is it that the number one side effect of anti depressants is suicide, thats kinda weird , no? lets talk about things. no one knows anything for sure.why did you even ask for help if you know everything? i want to help, i want ppl to be as happy as possible in this shit world. are you on something that makes you aggressive, like benzos?

yr argumentative, are you thinking yr trans?

also, seems like a joke but... asl?

...

>i said new research. old research is old
There is plenty of new research showing the effectiveness of medication and therapy.

>the number one side effect of anti depressants is suicide,
The number one side effect of antidepressants is dry mouth or dizziness, what are you on about.

Wanting to help is good but it's obvious that you don't know what you're talking about.
Arguing with you because your logic is obviously flawed is not aggression.

If someone says retarded stuff without any valid arguments or proof to back it up you're saying I should just nicely swallow their bullshit just because they're trying to help?

Have you considered the norepinephrine-dopamine reuptake inhibitor route?

Keep taking the SSRI but ask your doctor to add in Wellbutrin (Bupropion).

Wellbutrin doesn't get enough credit. When coupled with SSRIs it can be a game changer for a lot of people.

The SSRI will continue to work on serotonin but the Wellbutrin will add in an effect on norepinephrine and dopamine.

This will give you a weaker but similar effect to an MAOI as an MAOI interacts with all 3 of these neurotransmitters. The risks are much lower though as these medications are more targeted and the doses can be more easily adjusted.

This is entirely safe. Doctors prescribe this combination regularly.

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somehow, i think you are the reason for your own depression. i think you are a totally shit person, causing isolation and desperation. you are in the UK, no? we are in different timezones im not sober, not as articulate as you demand. not in the mood to recite references. i still feel bad for you, but not as much as i once did, and yet so much more so. did you really come on Any Forums for doctors to respond to you? no one loves you, and they probably never will. try 5-htp if you think there is brain chemical issues. i love you, and its all a contradiction.

like i asked before, talk about what makes you so sad here, this can be your therapy.

Wow you're a pretentious twat.

You think you know me cause you've read a couple of posts of mine wherein I disagree with your drunk babbling?

I'm not a "totally shit person", I just have a low tolerance towards people who act like they're experts on a topic they obviously don't know shit about or mostly only have personal experience with.

If you're not in the mood to cite references, don't make such wild claims.

Like I said: do you genuinely expect me to swallow your obvious bullshit just because you're "trying to help"?
It takes more than that to convince a person.

There is no direct cause for my anhedonia that is why I'm choosing to go for medication

kys

go back to red dit tranny!

Just take Adderall/Ritalin. Wellbutrin barely has an effect.

Wellbutrin doesn't suffer from the same tolerance issues and the dose can be more accurately tailored.

Adderall works quick but you build up a tolerance quick. That isn't helpful for depression. The constant dosing adjustments can lead to a slingshot effect.

You're also not going to easily get an Adderall script. They require a diagnosis from an ADHD specialist and that can take months depending on the route you take.

OP can get Wellbutrin tomorrow.