Previous thread• Help, advice, guidance on meds and dosages • HRT related medical experiences and research • Availability and pricing of medications • Rational and scientific discussion
I went on GnRH agonists two weeks ago. I'm still taking cypro and estrogen to suppress my testosterone, as before. I've been experiencing mood swings and fits of anger. Could it be that cypro isn't entirely blocking my now heightened testosterone levels, resulting in that, or is something else going on?
Robert Ward
Yeah, sounds like your cypro + estrogen isn't enough to suppress that initial T megaspike. which is normal desu - you'll go back to normal soon enough. I don't think you need to adjust dosages unless it gets worse or lasts more than few weeks
Elijah Gomez
That's such a relief. I was wondering what was going on with me. Why I was being so awful, like before transition. If it's that then that's great. Thank you.
I thought it was unlikely that my blockers couldn't suppress my levels but I'm glad I asked.
Christian Jones
how much cypro are you taking, out of curiosity
Angel Torres
10 mg/day, which was enough to suppress my testosterone levels beforehand
Daniel Gomez
endoshit concensus seems to be prescribing 12.5 for gnrh spike suppression, but desu i think 2.5mg is just not enough to make a difference
you'll be fine anyway - im sorry you feel like shit rn, but it's not going to have any consequences for your transition
Michael Myers
I currently inject 8mg EV every 5 days, but I'm planning on changeing it to 9mg EV every 7 days, which should give me a trough arround 250-275 more or less. does anyone have an equasion for figgureing out how many ml to inject to get your target amount of EV in mg? I figgured it out before but I totaly forgot how I did it and ive been scratching my head with a calculator for like half an hour now trying to work it out.
wait nevermind I figgured it out, in a backwards sorta screwball way
Nathaniel Cooper
Is there a difference between Spiro ACCOR and Spiro ZYDUS. Seems like different brand names but my new pills smell weird (haven't taken a new one yet).
Bentley Campbell
how bad is my trough being a bit over 400 for say... almost a year? clearly it hasnt hurt me but.... just how badis that?
EV is shit for a weekly cycle, get EC of EE instead
Gavin Myers
you sure? I'm looking at the injectable estradiol simulator and it looks like it'll work fine...I also have 5 years worth of EV so im reluctant to buy a new ester... whats the specific reason it isnt advised?
Elijah Lopez
Someone talked about estrogen powder in a different thread.. is there anything better about buying powder over buying a supplement like estrofem.. Like could I buy powder and make my own capsules (?) idkidk
..I don’t even start HRT yet btw.. I don’t know much about anything.. @.@ °○
Carson Martinez
the raw powder can indeed be used to make your own capsuels, injections, transdermal ointments, etc. it is far cheaper if you go that route but you will need a very precise scale to make measurement, normal estradiol pills are only 2mg, which is a VERRYYYY small ammount you're working with. it may be a lot easier to just buy pre-made pills, although it will cost more ofc
thank yuu.. I guess I need a good scale. .is there a good brand for scales ? Like.. how would I even start making 2mg capsules :o
Brayden Nguyen
if you're going to do EV do it every 3-5 days instead of every week, your highs and lows if you do a weekly cycle are gonna be bad, and you'll be forced to inject more than you should if you're worried about injecting too often, use some smaller gauge insulin needles and do subq
Luke Garcia
for capsules you would probably want to indavidualy mix 2mg with a filler of some kind (corn starch, sugar, whatever) to scoop into your capsuels, if you look arround on ebay and other places you can find trays to hold sets of capsules as you fill them. you could try the little digital drug-dealer scales you find at shady gas stations, but a nicer scale from a medical/scientific instrument vendor would probably be best. honestly unless money is a serious issue or you plan on selling homebrew hrt to others, I would advise you stick with just buying pre-made stuff, at least until you start injections, then it may very well be worth your while
Austin Gonzalez
from what im looking at it's lows should be in the range I want, and the highs are only ~30-50pg/mL lower than my current highs I get from 8mg every 5 days. I already do sq and use small gauge needles atm. from what im looking at it seems the spikes will be slightly less high and the trough will be in a more acceptable range. but actualy as im typing that im wondering if its more the difference between trough and peak that would cause discomfort?
